Molecular Virology, Research & Development - San Francisco, CA
LabCorp is seeking an enthusiastic and innovative Scientist willing to engage integrated, cross disciplinary teams to develop and commercialize novel assay systems that are designed to evaluate the activity and efficacy of viral vector directed gene therapy, antiviral drug therapy and preventative or therapeutic viral vaccines. This Scientist will also contribute to coordinated R&D and Clinical Research efforts directed at establishing the clinical validity and defining the appropriate clinical utility of newly developed assays.
The principal responsibilities of this Scientist position include the innovation, development, optimization and analytical validation of novel molecular and cell-based infectivity assays that predict and characterize responses to (a) viral vector-mediated gene therapy, (b) novel antiviral therapies, and (c) vaccination against emerging viral infections. The initiatives of this position will be directed at the realization of significant immediate and near term revenue opportunities including (a) pre-clinical evaluations, (b) clinical trials, (c) routine CLIA laboratory diagnostic testing (LDTs), and (d) FDA-approved companion diagnostics (IVD CDx).
Principal responsibilities of this position include:
- The design, development, optimization, scale up and validation of cell-based and molecular assays,
- The application of these technologies to support clinical trials and research projects, including participating in and coordinating internal studies or external collaborations to define and validate the clinical utility of Monogram's assays and
- To interrogate mechanisms of drug activity and resistance, antibody neutralization and viral pathogenesis.
- Graduate Degree in Molecular Biology, Virology or related area of Biological Sciences
- Minimum 2-5 years of experience working in Molecular Biology
- Proficiency in cell and molecular virology techniques, including cell culture, cell based infectivity assays, nucleic acid amplification, molecular cloning, and nucleic acid sequencing and sequence analysis
- Ability to independently design, conduct and analyze critical experiments that further project goals
- Previous experience in assay development is strongly preferred
- Quick to master new techniques and ability to multitask
- High technical proficiency and attention to detail
- Strong organizational, record keeping, data analysis and computational skills
- Ability to work within a fast paced and highly collaborative environment
- Strong written and oral presentation skills
- Doctoral Degree in Molecular Biology, Virology or related area of Biological Sciences
- Experience working with pharmaceutical industry